Weeds can germinate between pavers from windblown seeds lodged in the joints; they don’t grow from the bedding sand, base or soil. Weeds can be removed by hand or with herbicides. Take care in using herbicides so that adjacent vegetated areas are not damaged. Use biodegradable products that won’t damage other vegetation or pollute water supplies when washed from the pavement surface. Besides stabilizing the joint sand, sealers can prevent seeds from germinating, and prevent ants from entering.